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Product Name
Human CENPC1 Recombinant protein (GST tag)
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Description
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions. {PubMed:19482874, PubMed:21529714}.
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Protein name
Centromere protein C
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Protein short names
CENPC1; ICEN7
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Uniprot ID
Q03188
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Gene Name
CENPC; CENPC1; ICEN7
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human CENPC (NP_001803.2) 598-943 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human CENPC1 SDS-PAGE
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