Human CENPA Recombinant protein (GST tag)

Cat.#: 506497

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Product Information

  • Product Name
    Human CENPA Recombinant protein (GST tag)
  • Documents
  • Description
    Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro). {PubMed:20739937, PubMed:21478274}.
  • Protein name
    Histone H3-like centromeric protein A
  • Uniprot ID
    P49450
  • Gene Name
    CENPA
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    1-59 aa encoded by NM_001809 was inserted into PGEX-4T vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human CENPA SDS-PAGE

    Recombinant human CENPA SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"