Human CDK2AP2/DOC1R (His tag) recombinant protein

Human CDK2AP2/DOC1R (His tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

CDK2AP2, also known as DOC1R, is short for cyclin-dependent kinase 2-associated protein 2. The gene CDK2AP2 encodes this protein that interacts with cyclin-dependent kinase 2 associated protein 1. Pseudogenes associated with this gene are located on chromosomes 7 and 9. Alternatively spliced transcript variants have been observed for this gene. It belongs to the CDK2AP family. CDK2AP1 (cyclin-dependent kinase 2-associated protein 1), corresponding to the gene doc-1 (deleted in oral cancer 1), is a tumor suppressor protein. The doc-1 gene is absent or down-regulated in hamster oral cancer cells and in many other cancer cell types. The ubiquitously expressed CDK2AP1 protein is the only known specific inhibitor of CDK2, making it an important component of cell cycle regulation during G(1)-to-S phase transition.

cyclin dependent kinase 2 associated protein 2(CDK2AP2)

DOC1R

O75956

Human Cells

A DNA sequence encoding the Human CDK2AP2/DOC1R Met1-Thr126 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.