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Product Name
Human CDC73/C1orf28/HRPT2 (His tag) recombinant protein
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Description
Parafibromin is expressed in the adrenal and parathyroid glands, kidney, and heart. As a tumor supressor, Parafibromin may be involved in transcriptional and post-transcriptional control pathways, also through the regulation of cyclin D1/PRAD1 expression, involved the cell cycle progression. Parafibromin is a component of the the PAF protein complex and interacts with a Set1-like complex that has histone methyltransferase activity and methylates histone H3. Defects in Parafibromin can cause hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
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Protein name
cell division cycle 73(CDC73)
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Protein short names
C1orf28; HRPT2
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Uniprot ID
Q6P1J9
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CDC73/C1orf28/HRPT2 Met1-Glu260 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CDC73/C1orf28/HRPT2 (His tag) recombinant protein
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