-
Product Name
Human CDC73/C1orf28/HRPT2 (His tag) recombinant protein
- Documents
-
Description
Parafibromin is expressed in the adrenal and parathyroid glands, kidney, and heart. As a tumor supressor, Parafibromin may be involved in transcriptional and post-transcriptional control pathways, also through the regulation of cyclin D1/PRAD1 expression, involved the cell cycle progression. Parafibromin is a component of the the PAF protein complex and interacts with a Set1-like complex that has histone methyltransferase activity and methylates histone H3. Defects in Parafibromin can cause hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
-
Protein name
cell division cycle 73(CDC73)
-
Protein short names
C1orf28; HRPT2
-
Uniprot ID
Q6P1J9
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the Human CDC73/C1orf28/HRPT2 Met1-Glu260 is expressed with a 6His tag at the N-terminus.
-
Protein Species
Human
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Human CDC73/C1orf28/HRPT2 (His tag) recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"