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Product Name
Human CD209/CLEC4L (Fc tag) recombinant protein
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Description
CD209 antigen（CD209）contains 1 C-type lectin domain. Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates. CD209 may act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2. It seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells.
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Protein name
CD209 molecule(CD209)
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Protein short names
CLEC4L
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Uniprot ID
Q9NNX6
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CD209/CLEC4L Lys62-Ala404 is expressed with a Fc tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CD209/CLEC4L (Fc tag) recombinant protein
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