Human CCDC99 Recombinant protein (GST tag)

Cat.#: 506313

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Product Information

  • Product Name
    Human CCDC99 Recombinant protein (GST tag)
  • Documents
  • Description
    Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. {HAMAP-Rule:MF_03041, PubMed:17576797, PubMed:19468067}.
  • Protein name
    Protein Spindly
  • Protein short names
    CCDC99
  • Uniprot ID
    Q96EA4
  • Gene Name
    SPDL1; CCDC99
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human SPDL1 (XP_054208849.1) 259-605 aa was fused with the N-terminal GST tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human CCDC99 SDS-PAGE

    Recombinant human CCDC99 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"