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Product Name
Human CAPN2/CANPL2 (His tag) recombinant protein
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Description
Calpain-2 Catalytic Subunit (CANP2) is an intracellular cysteine protease. It contains 1 calpain catalytic domain and 3 EF-hand domains. CANP2 is a member of the peptidase C2 family of intracellular Ca2+-regulated cysteine proteases. These ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits (CANP2) associated with a common small, regulatory subunit (CAPNS1). CANP2 is activated by 200-1000 micromolar concentrations of calcium and inhibited by calpastatin. CANP2 is calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
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Protein name
calpain 2(CAPN2)
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Protein short names
CANPL2
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Uniprot ID
P17655
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CAPN2/CANPL2 Met1-Leu700 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CAPN2/CANPL2 (His tag) recombinant protein
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