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Human C13orf3 Recombinant protein (His tag)

Cat.#: 505924

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Special Price 294.7 USD

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Product Information

  • Product Name
    Human C13orf3 Recombinant protein (His tag)
  • Documents
  • Description
    Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:19289083, PubMed:19360002, PubMed:23085020). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083, PubMed:19360002). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). In the complex, it mediates the microtubule-stimulated oligomerization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020). {PubMed:19289083, PubMed:19360002, PubMed:23085020}.
  • Protein name
    Spindle and kinetochore-associated protein 3
  • Protein short names
    C13orf3; RAMA1
  • Uniprot ID
    Q8IX90
  • Gene Name
    SKA3; C13orf3; RAMA1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human SKA3 (NP_659498.4) 1-356 aa was fused with the polyhistidine tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human C13orf3 SDS-PAGE

    Recombinant human C13orf3 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"