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Product Name
Human BTG2 Recombinant protein (GST tag)
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Description
Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth. {, PubMed:12771185, PubMed:15788397, PubMed:18337750, PubMed:18773938, PubMed:23236473}.
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Protein name
Protein BTG2
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Protein short names
PC3
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Uniprot ID
P78543
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Gene Name
BTG2; PC3
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
1-50 aa encoded by NM_006763 was inserted into PGEX-4T vector
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human BTG2 SDS-PAGE
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