Human BPI (His tag) recombinant protein

Human BPI (His tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Bactericidal permeability-increasing protein(BPI for short), is a secreted protein which belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family. It exists as a monomer or a disulfide-linked homodimer. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria. This specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. BPI has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, and this activity is inhibited by LPS from P.aeruginosa.

bactericidal/permeability-increasing protein(BPI)

P17213

Human Cells

A DNA sequence encoding the Human BPI Val32-Lys487 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.