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Product Name
Human BPGM (His tag) recombinant protein
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Description
Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. It also has phosphoglycerate phosphomutase activity. BPGM plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Deficiency of BPGM increases the affinity of cells for oxygen and result in hemolytic anemia.
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Protein name
bisphosphoglycerate mutase(BPGM)
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Uniprot ID
P07738
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human BPGM Ser2-Lys259 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human BPGM (His tag) recombinant protein
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