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Product Name
Human BNIP3/NIP3 (His tag) recombinant protein
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Description
BCL2/Adenovirus E1B 19 kDa Protein-Iinteracting Protein 3 (BNIP3) is a single-pass membrane protein. BNIP3 is a member of the NIP3 family. BNIP3 contains a single Bcl-2 homology 3 domain and interacts with the E1B 19 kDa protein. BNIP3 have been associated with pro-apoptotic function. BNIP3 is an apoptosis-inducing protein that can overcome BCL2 suppression. It plays a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. BNIP3 involved in mitochondrial quality control via its interaction with SPATA18/MIEAP, response to mitochondrial damage, participates to mitochondrial protein catabolic process.
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Protein name
BCL2 interacting protein 3(BNIP3)
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Protein short names
NIP3
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Uniprot ID
Q12983
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human BNIP3/NIP3 Met1-Leu166 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human BNIP3/NIP3 (His tag) recombinant protein
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