-
Product Name
Human BAX/BCL2L4 (His tag) recombinant protein
- Documents
-
Description
Apoptosis Regulator BAX (BAX) belongs to the Bcl-2 family. BAX exists as a homodimer and is expressed in a wide variety of tissues. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa). Although both isoforms contain BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. BAX accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. BAX also promotes activation of CASP3, and thereby apoptosis.
-
Protein name
BCL2 associated X, apoptosis regulator(BAX)
-
Protein short names
BCL2L4
-
Uniprot ID
Q07812
-
Source/Expression Host
E.coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the Human BAX/BCL2L4 Met1-Gln171 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
-
Protein Species
Human
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Human BAX/BCL2L4 (His tag) recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"