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Product Name
Human BAG2 (His tag) recombinant protein
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Description
BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
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Protein name
BCL2 associated athanogene 2(BAG2)
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Uniprot ID
O95816
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human BAG2 Met1-Asn211 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human BAG2 (His tag) recombinant protein
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