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Product Name
Human ATG4A/APG4A/AUTL2 (His tag) recombinant protein
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Description
Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.
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Protein name
autophagy related 4A cysteine peptidase(ATG4A)
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Protein short names
APG4A; AUTL2
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Uniprot ID
Q8WYN0
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human ATG4A/APG4A/AUTL2 Met1-Val398 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human ATG4A/APG4A/AUTL2 (His tag) recombinant protein
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