Human ARL13B Recombinant protein (GST tag)

Human ARL13B Recombinant protein (GST tag)

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Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic; however, additional evidences are required to confirm these data. {PubMed:23150559}.

ADP-ribosylation factor-like protein 13B

ARL2L1

Q3SXY8

ARL13B; ARL2L1

E. coli

A DNA sequence encoding the human ARL13B (NP_659433.2) 1-321 aa was fused with the N-terminal GST tag

Human

Not tested.