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Product Name
Human APLNR Recombinant protein (GST tag)
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Description
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.
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Protein name
Apelin receptor
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Protein short names
AGTRL1; APJ
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Uniprot ID
P35414
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Gene Name
APLNR; AGTRL1; APJ
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human APLNR (NP_005152.1) 301-380 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human APLNR SDS-PAGE
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