Human ANTXR1/ATR/TEM8 (His tag) recombinant protein

Cat.#: 518487

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Product Information

  • Product Name
    Human ANTXR1/ATR/TEM8 (His tag) recombinant protein
  • Documents
  • Description
    Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It is also involved in the angiogenic response of cultured umbilical vein endothelial cells, up-regulated in cultured angiogenic umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI).
  • Protein name
    anthrax toxin receptor 1(ANTXR1)
  • Protein short names
    ATR; TEM8
  • Uniprot ID
    Q9H6X2
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human ANTXR1/ATR/TEM8 Glu33-Lys321 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human ANTXR1/ATR/TEM8 (His tag) recombinant protein

    Human ANTXR1/ATR/TEM8 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"