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Product Name
Human ANTXR1 (Fc Tag) recombinant protein
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Description
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.
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Protein name
Anthrax toxin receptor 1
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Protein short names
ANTRX1; 2810405N18RIK; FLJ11298; 2310008J16RIK; TEM8; TUMOR ENDOTHELIAL MARKER 8; FLJ21776; GAPO; FLJ10601; ATR
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Uniprot ID
Q9H6X2
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Gene Name
ANTXR1; ATR; TEM8
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human ANTXR1 (Q9H6X2-4) (Met1-Ser321) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human ANTXR1 /Fc is a disulfide-linked homodimer. The reduced monomer comprises 530 amino acids and has a predicted molecular mass of 59.4 kDa. The apparent molecular mass of the protein is approximately 69 kDa in SDS-PAGE under reducing conditions.
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Purity
> 92 % as determined by SDS-PAGE
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Validations
Human ANTXR1 Protein (Fc Tag) SDS-PAGE
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