-
Product Name
Human AKR1C4/CHDR (His tag) recombinant protein
- Documents
-
Description
Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-α-Androstan-3-α,17-β-diol (3-α-diol). In addition, AKR1C4 also has some 20-α-Hydroxysteroid Dehydrogenase activity.
-
Protein name
aldo-keto reductase family 1 member C4(AKR1C4)
-
Protein short names
CHDR
-
Uniprot ID
P17516
-
Source/Expression Host
E.coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the Human AKR1C4/CHDR Met1-Tyr323 is expressed with a 6His tag at the N-terminus.
-
Protein Species
Human
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Human AKR1C4/CHDR (His tag) recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"