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Product Name
Human AID Recombinant protein (His tag)
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Description
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. {PubMed:18722174, PubMed:21385873, PubMed:21496894, PubMed:21518874}.
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Protein name
Single-stranded DNA cytosine deaminase
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Protein short names
AID
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Uniprot ID
Q9GZX7
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Gene Name
AICDA; AID
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human AICDA (NP_065712.1) 1-198 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human AID SDS-PAGE
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