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Product Name
HuA/B/C/D antibody
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Description
HuA/B/C/D Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in human cerebellum tissue, mouse cerebellum tissue, PC-13 cells. Positive IHC detected in human breast cancer tissue. Observed molecular weight by Western-blot: 40 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human,Mouse,Rat,Zebrafish; other species not tested.
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Alternative names
ELAV like protein 4 antibody; ELAVL4 antibody; Hu antigen D antibody; Hu C/D antibody; HUD antibody; PNEM antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of HuA/B/C/D recombinant protein (Accession Number: NM_001144774). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IP: 1:200-1:1000
IHC: 1:20-1:200
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Validations
human cerebellum tissue were subjected to SDS PAGE followed by western blot with Catalog No:111717(ELAVL4 antibody) at dilution of 1:800
Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:111717(ELAVL4 antibody) at dilution of 1:100 (under 10x lens)
IP Result of anti-ELAVL4 (IP:Catalog No:111717, 4ug; Detection:Catalog No:111717 1:300) with mouse brain tissue lysate 2560ug.
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Background
Embryonic lethal, abnormal vision, Drosophila-like 4 (ELAVL4) is a human homologue of the Drosophilia gene ELAV, which is implicated in neuronal differentiation and maintenance. The ELAVL proteins are mRNA binding proteins and all members of the family contain three RNA-recognition motifs [PMID:12402251]. ELAVL-proteins also interact with inflammation-associated factors. The protein may be implicated in neurodegeneration through these complex mechanisms [PMID:15827745].
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