HSP70 antibody

HSP70 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

HSP70 Rabbit Polyclonal antibody. Positive IP detected in K-562 cells. Positive WB detected in K-562 cells. Observed molecular weight by Western-blot: 60-70 kDa

ELISA, WB, IP

Human, Mouse, Rat; other species not tested.

Heat shOCk 70 kDa protein 1/2 antibody; HSP70 antibody; HSPA1 antibody; HSPA1A antibody; HSPA1B antibody

Rabbit IgG

This antibody was obtained by immunization of HSP70 recombinant protein (Accession Number: NM_005345). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

HSP70 (also referred to HSP72), is a stress-inducible member of heat-shock protein 70 (HSP70) proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSP70 is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Generally, HSP70 is thought to be expressed in unstressed normal cells at low or undetectable levels. Expression of HSP70 protein can be highly activated by various stressful stimuli. Significant up-regulation of HSP70 has been found in various tumors. Recently it has been reported that HSP70 can be constitutively expressed in selected cell types. This antibody recognizes two isoforms of HSP70 around 70 kDa and 60 kDa, respectively.