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Product Name
HMMR Polyclonal Antibody
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Description
Polyclonal antibody to HMMR
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Tested applications
WB, IF
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Species reactivity
Human
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Alternative names
HMMR antibody; CD168 antibody; IHABP antibody; RHAMM antibody; hyaluronan mediated motility receptor antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human HMMR (NP_001136028.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IF 1:50 - 1:200 -
Validations
Western blot - HMMR Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using HMMR antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Immunofluorescence - HMMR Polyclonal Antibody
Immunofluorescence analysis of U2OS cells using HMMR antibody . Blue: DAPI for nuclear staining.
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Background
Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"