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Product Name
HLA-E antibody
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Description
HLA-E Rabbit Polyclonal antibody. Positive WB detected in human liver tissue, human kidney tissue. Observed molecular weight by Western-blot: 40kd
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
DKFZp686P19218 antibody; EA1.2 antibody; EA2.1 antibody; HLA 6.2 antibody; HLA E antibody; HLAE antibody; HLA-E antibody; MHC antibody; MHC class I antigen E antibody; QA1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of HLA-E recombinant protein (Accession Number: NM_005516). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:111429(HLA-E antibody) at dilution of 1:500
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Background
Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). There are two classes of HLA antigens: class I and class II. This class I molecules are membrane glycoproteins composed of a heavy (alpha) chain which is encoded by a HLA class I gene, and β2-microglobulin light (beta) chain. The most extensively characterized members of the HLA class I gene family are the genes encoding the major transplantation antigenes, HLA-A, B and C. HLA-E is a non-classical MHC class I molecule. (PMID: 667938; 3375250; 2249951)
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