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Product Name
Human SMYD3 (His & FLAG Tag) recombinant protein
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Description
Histone methyltransferase. Specifically methylates 'Lys-4' and 'Lys-5' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.
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Protein name
Histone-lysine N-methyltransferase SMYD3
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Protein short names
ZNFN3A1; KMT3E; BA74P14.1; 2410008A19RIK; MGC104324; FLJ21080; ZMYND1; SMYD3
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Uniprot ID
Q9H7B4
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Gene Name
SMYD3; ZMYND1; ZNFN3A1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human SMYD3 isoform 1 (NP_001161212.1) (Met 1-Ser 428) was fused with the flag tag at the N-terminus. and the Histidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human SMYD3 consists of 447 amino acids and predicts a molecular mass of 51.5 kDa. It migrates as an approxiamtely 49 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human SMYD3 / ZMYND1 Protein (His & FLAG Tag) SDS-PAGE
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