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Product Name
HIST2H2AA4 Polyclonal Antibody
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Description
Polyclonal antibody to HIST2H2AA4
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Tested applications
WB
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Species reactivity
Human
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Alternative names
HIST2H2AA4 antibody; H2A/R antibody; histone H2A type 2-A antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic Peptide of human HIST2H2AA4
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
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Validations
Western blot - HIST2H2AA4 Polyclonal Antibody
Western blot analysis of extracts of MDA-MB231 cells, using HIST2H2AA4 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"