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Product Name
HIST1H1C Polyclonal Antibody
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Description
Polyclonal antibody to HIST1H1C
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Tested applications
WB
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Species reactivity
Human
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Alternative names
HIST1H1C antibody; H1.2 antibody; H1C antibody; H1F2 antibody; H1s-1 antibody; histone H1.2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human HIST1H1C
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - HIST1H1C Polyclonal Antibody
Western blot analysis of extracts of HeLa cells, using HIST1H1C antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"