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Product Name
Human CD64/FCGR1 (His Tag) recombinant protein
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Description
High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
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Protein name
High affinity immunoglobulin gamma Fc receptor I
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Protein short names
FCGAMMARI; IGFR1; CD64; FCGR1C; FCGR1B; AV092959; IGFRB; FCRI; RP11-439A17.1; AI323638; FCGR1; FLJ18345; IGGHAFC; FCGR1A; IGFRC
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Uniprot ID
P12314
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Gene Name
FCGR1A; FCG1; FCGR1; IGFR1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain of human CD64A (NP_000557.1) (Met 1-Pro 288) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CD64A consists of 284 amino acids and has a predicted molecular mass of 32 kDa.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA.
1. Immobilized CD64 at 10 μg/ml can bind human IgG1 with a linear range of 0.39-25 ng/ml.
2. Scatchard analysis showed the affinity constant (Kd) of CD64 bound to Human IgG1 was 0.059 nM. -
Validations
Human CD64 / FCGR1A Protein (His Tag)
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