Anti-CD64/FCGR1 antibody

Anti-CD64/FCGR1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit monoclonal to CD64/FCGR1

FCM

Rat CD64 / FCGR1

AI323638 antibody; AV092959 antibody; CD64 antibody; CD64 antibody; FcgammaRI antibody; Fcgr1 antibody; FCGR1 antibody; FCGR1A antibody; FCGR1B antibody; FCGR1C antibody; FCRI antibody; FLJ18345 antibody; IGFR1 antibody; IGFRB antibody; IGFRC antibody; IGGHAFC antibody; RP11-439A17.1 antibody

Rabbit IgG

This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD64 / FCGR1 (rR CD64 / FCGR1; NP_001094306.1; Met1-Pro285) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

Monoclonal

Aqueous solution containing 0.5% BSA and 0.09% sodium azide

This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

FCM

High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membrane glycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of a signal peptide that allows its transport to the surface of a cell, three extracellular immunoglobulin domains of the C2-type that it uses to bind antibody, a hydrophobic transmembrane domain, and a short cytoplasmic tail. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses.