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Product Name
Hephaestin antibody
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Description
Hephaestin Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue.
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Tested applications
ELISA, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CPL antibody; HEPH antibody; Hephaestin antibody; KIAA0698 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Hephaestin recombinant protein (Accession Number: NM_001367233). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:111292(HEPH antibody) at dilution of 1:50 (under 10x lens)
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Background
Hephaestin, also named as KIAA0698, belongs to the multicopper oxidase family. It is provied as ferroxidase of cellular iron export. HEPH is implicated in iron homeostasis and may mediate iron efflux associated to ferroportin 1. HEPE is active in placenta but may not play a key role in placental iron transport.
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References
- Li YQ, Bai B, Cao XX, Yan H, Zhuang GH. Ferroportin 1 and hephaestin expression in BeWo cell line with different iron treatment. Cell biochemistry and function. 30(3):249-55. 2012.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"