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Product Name
Human Hemopexin (His Tag) recombinant protein
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Description
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
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Protein name
Hemopexin
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Protein short names
HX; HPX; FLJ56652; HPXN; HEMOPEXIN
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Uniprot ID
Q9BS19
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Gene Name
HPX
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human HPX (NP_000604.1) (Met 1-His 462) with a C-terminal polyhistidine tag was expressed.
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Protein Species
Human
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Molecular weight
The secreted recombinant human HPX comprises 450 amino acids with a predicted molecular mass of 50.7 kDa. As a result of glycosylation, rhHPX migrates as an approximately 70-75 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 96 % as determined by SDS-PAGE
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Activity
Measured by its ability to bind protoporphyrin IX (PPPIX). Recombinant human Hemopexin binds > 10 μM PPPIX, resulting in a 50% decrease in the fluorescence signal of human Hemopexin.
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Validations
Human Hemopexin / HPX Protein (His Tag) SDS-PAGE
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