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Product Name
HDAC1 antibody
- Documents
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Description
HDAC1 Mouse Monoclonal antibody. Positive WB detected in Hela cells, HEK-293 cells, HepG2 cells, Jurkat cells. Observed molecular weight by Western-blot: 65kD
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
DKFZp686H12203 antibody; GON 10 antibody; HD1 antibody; HDAC1 antibody; histone deacetylase 1 antibody; RPD3 antibody; RPD3L1 antibody
- Immunogen
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of HDAC1 recombinant protein (Accession Number: NM_004964). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:107257(HDAC1 antibody) at dilution of 1:4000
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Background
Histone deacetylases(HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex, which is responsible for gene expression silencing. It also plays an important role in the control of cell proliferation and differentiation by interacting with RB, p53 and other transcription factors. At least 4 classes of HDAC were identified. As a class I HDAC, HDAC 1 was primarily found in the nucleus. This antibody is raised against residues near the C terminus of human HDAC1.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"