GUCY2D antibody

GUCY2D antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

GUCY2D Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, human brain tissue. Observed molecular weight by Western-blot: 120kd,95kd

ELISA, WB

human, mouse, rat; other species not tested.

GUCY2D antibody; CYGD antibody; Guanylate cyclase 2D antibody; retinal antibody; GUC1A4 antibody; LCA1 antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_000180). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

GUCY2D, also named as CORD6, GUC1A4, GUC2D, RETGC, RETGC1 and ROS-GC, belongs to the adenylyl cyclase class-4/guanylyl cyclase family. It probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. A number of nonsense and frameshift mutations in the GUCY2D gene have been identified in LCA1 patients. Defects in GUCY2D are the cause of cone-rod dystrophy type 6 (CORD6). GUCY2D is responsible for many reported cases of autosomal dominant CRDs. The antibody is specific to GUCY2D.