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Product Name
Human RHEB / RHEB2 (His Tag) recombinant protein
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Description
Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity.
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Protein name
GTP-binding protein Rheb
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Protein short names
RHEB; GTP-BINDING PROTEIN RHEB; RHEB2; RAS HOMOLOG ENRICHED IN BRAIN 2; RAS HOMOLOG ENRICHED IN BRAIN; RHEB1
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Uniprot ID
Q15382
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Gene Name
RHEB; RHEB2
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human RHEB (Q15382)(Met1-Cys181) was fused with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human RHEB consists of 199 amino acids and has a calculated molecular mass of 22.4 kDa. The recombinant protein migrates as an approximately 21 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human RHEB Protein (His Tag) SDS-PAGE
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