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Product Name
GSPT2 Polyclonal Antibody
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Description
Polyclonal antibody to GSPT2
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Tested applications
WB
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Species reactivity
Human, Mouse
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Alternative names
GSPT2 antibody; ERF3B antibody; GST2 antibody; G1 to S phase transition 2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic Peptide of human GSPT2
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
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Validations
Western blot - GSPT2 Polyclonal Antibody
Western blot analysis of extracts of 293T cells, using GSPT2 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"