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Product Name
GSNOR,ADH5 antibody
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Description
GSNOR,ADH5 Mouse Monoclonal antibody. Positive IHC detected in human pancreas cancer tissue, human testis tissue. Positive IF detected in HepG2 cells. Positive WB detected in fetal human brain tissue, human testis tissue. Observed molecular weight by Western-blot: 40 kDa
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Tested applications
ELISA, IHC, IF, WB
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Species reactivity
Human; other species not tested.
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Alternative names
ADH 3 antibody; ADH5 antibody; ADHX antibody; Alcohol dehydrogenase 5 antibody; Alcohol dehydrogenase class 3 antibody; FALDH antibody; FDH antibody; GSH FDH antibody; GSNOR antibody; GSNOR antibody; ADH5 antibody
- Immunogen
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of GSNOR,ADH5 recombinant protein (Accession Number: NM_000671). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IHC: 1:20-1:200
IF: 1:20-1:200
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Validations
fetal human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:107307(GSNOR,ADH5 Antibody) at dilution of 1:4000
Immunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using Catalog No:107307(GSNOR,ADH5 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using Catalog No:107307(GSNOR,ADH5 Antibody) at dilution of 1:50 (under 40x lens)
Immunofluorescent analysis of HepG2 cells using Catalog No:107307(GSNOR,ADH5 Antibody) at dilution of 1:50 and Rhodamine-Goat anti-Mouse IgG
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Background
ADH5, also named as ADHX, FDH FALDH GSH-FDH ADH3 and GSNOR, belongs to the zinc-containing alcohol dehydrogenase family and Class-III subfamily. It is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. ADH5 mediates multiple cardiovascular functions. It plays in regulating heterocellular communication in the artery wall. (PMID:21071693). ADH5 immunostaining is distributed in both the nucleus and cytoplasm of the retinal ganglion cells(PMID:22117533).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"