GRWD1 antibody

Cat.#: 111163

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Product Information

  • Product Name
    GRWD1 antibody
  • Documents
  • Description
    GRWD1 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive WB detected in HEK-293 cells, PC-3 cells, SKOV-3 cells. Observed molecular weight by Western-blot: 49kd
  • Tested applications
    ELISA, IHC, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    GRWD antibody; GRWD1 antibody; KIAA1942 antibody; RRB1 antibody; WDR28 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of GRWD1 recombinant protein (Accession Number: NM_031485). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:111163(GRWD1 Antibody) at dilution of 1:600

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:111163(GRWD1 Antibody) at dilution of 1:600

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:111163(GRWD1 antibody) at dilution of 1:100 (under 25x lens)

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:111163(GRWD1 antibody) at dilution of 1:100 (under 25x lens)

  • Background
    WD-repeat proteins are a class of functionally divergent molecules that cooperate with other proteins to regulate cellular processes. WD-repeat proteins have been implicated in a variety of cellular functions that are mostly regulatory in nature, including cytoskeleton organization, vesicular fusion, pre-mRNA splicing, and cell cycle regulation. WD-repeat-containing protein designated glutamate-rich WD repeat (GRWD1) is a component of the 50S and 80S preribosomal complexes and plays a role in ribosome biogenesis and during myeloid differentiation its levels are regulated. [PMID:15885502]

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"