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Product Name
GRM5 Monoclonal Antibody
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Description
Monoclonal antibody to GRM5
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Tested applications
WB, IHC, IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
GRM5 antibody; GPRC1E antibody; MGLUR5 antibody; PPP1R86 antibody; mGlu5 antibody; metabotropic glutamate receptor 5 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human GRM5
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200 -
Validations
Immunohistochemistry - GRM5 Monoclonal Antibody
Immunohistochemistry of paraffin-embedded mouse brain using GRM5 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - GRM5 Monoclonal Antibody
Immunohistochemistry of paraffin-embedded rat brain using GRM5 antibody at dilution of 1:100 (40x lens).
Immunofluorescence - GRM5 Monoclonal Antibody
Immunofluorescence analysis of SHG-44 cells using GRM5 antibody .
Immunofluorescence - GRM5 Monoclonal Antibody
Immunofluorescence analysis of JAR cells using GRM5 antibody .
Immunofluorescence - GRM5 Monoclonal Antibody
Immunofluorescence analysis of PC-12 cells using GRM5 antibody .
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Background
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"