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Product Name
GRM1 Polyclonal Antibody
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Description
Polyclonal antibody to GRM1
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Tested applications
WB, IHC
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Species reactivity
Human
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Alternative names
GRM1 antibody; GPRC1A antibody; MGLU1 antibody; MGLUR1 antibody; PPP1R85 antibody; SCAR13 antibody; metabotropic glutamate receptor 1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human GRM1
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
IHC 1:50 - 1:100 -
Validations
Western blot - GRM1 Polyclonal Antibody
Western blot analysis of extracts of human brain, using GRM1 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"