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GPX5 antibody

Cat.#: 111150

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Special Price 239.0 USD

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Product Information

  • Product Name
    GPX5 antibody
  • Documents
  • Description
    GPX5 Rabbit Polyclonal antibody. Positive IHC detected in human testis. Positive WB detected in human testis tissue, mouse liver tissue. Observed molecular weight by Western-blot: 25kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    human; other species not tested.
  • Alternative names
    GPX5 antibody; GSHPx 5 antibody; Glutathione peroxidase 5 antibody; GPx 5 antibody; EGLP antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_001509). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    human testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:111150(GPX5 antibody) at dilution of 1:200

    human testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:111150(GPX5 antibody) at dilution of 1:200

    Immunohistochemical of paraffin-embedded human testis using Catalog No:111150(GPX5 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human testis using Catalog No:111150(GPX5 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human testis using Catalog No:111150(GPX5 antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human testis using Catalog No:111150(GPX5 antibody) at dilution of 1:50 (under 40x lens)

  • Background
    GPX5 belongs to the glutathione peroxidase family. GPX5 protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. Catalytic the reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O. GPX5 constitute a glutathionine peroxidase-like protective system against peroxide damage in sperm membrane lipids.
  • References
    • Vilagran I, Yeste M, Sancho S, Castillo J, Oliva R, Bonet S. Comparative analysis of boar seminal plasma proteome from different freezability ejaculates and identification of Fibronectin 1 as sperm freezability marker. Andrology. 3(2):345-56. 2015.
    • Vilagran I, Castillo-Martín M, Prieto-Martínez N, Bonet S, Yeste M. Triosephosphate isomerase (TPI) and epididymal secretory glutathione peroxidase (GPX5) are markers for boar sperm quality. Animal reproduction science. 165:22-30. 2016.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"