-
Product Name
GP9 antibody
- Documents
-
Description
GP9 Rabbit Polyclonal antibody. Positive WB detected in human blood tissue. Positive IHC detected in human spleen tissue. Observed molecular weight by Western-blot: 17-22 kDa
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human; other species not tested.
-
Alternative names
CD42a antibody; Glycoprotein 9 antibody; glycoprotein IX (platelet) antibody; GP IX antibody; GP9 antibody; GPIX antibody; Platelet glycoprotein IX antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of GP9 recombinant protein (Accession Number: NM_000174). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
-
Validations
Immunohistochemistry of paraffin-embedded human spleen tissue slide using Catalog No:111055(GP9 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human spleen tissue slide using Catalog No:111055(GP9 Antibody) at dilution of 1:50 (under 40x lens)
human blood tissue were subjected to SDS PAGE followed by western blot with Catalog No:111055(GP9 Antibody) at dilution of 1:1000
-
Background
Platelet glycoprotein IX (GP9, also known as CD42a) is a relatively small (17-22 kDa) surface glycoprotein present on platelets and megakaryocytes. GP9 forms a 1:1 non-covalent complex with GPIb (CD42b). The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. Defects in GP9 are a cause of Bernard-Soulier syndrome, also known as giant platelet disease.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"