GP9 antibody

Cat.#: 111055

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Product Information

  • Product Name
    GP9 antibody
  • Documents
  • Description
    GP9 Rabbit Polyclonal antibody. Positive WB detected in human blood tissue. Positive IHC detected in human spleen tissue. Observed molecular weight by Western-blot: 17-22 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    CD42a antibody; Glycoprotein 9 antibody; glycoprotein IX (platelet) antibody; GP IX antibody; GP9 antibody; GPIX antibody; Platelet glycoprotein IX antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of GP9 recombinant protein (Accession Number: NM_000174). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    Immunohistochemistry of paraffin-embedded human spleen tissue slide using Catalog No:111055(GP9 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human spleen tissue slide using Catalog No:111055(GP9 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human spleen tissue slide using Catalog No:111055(GP9 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human spleen tissue slide using Catalog No:111055(GP9 Antibody) at dilution of 1:50 (under 40x lens)

    human blood tissue were subjected to SDS PAGE followed by western blot with Catalog No:111055(GP9 Antibody) at dilution of 1:1000

    human blood tissue were subjected to SDS PAGE followed by western blot with Catalog No:111055(GP9 Antibody) at dilution of 1:1000

  • Background
    Platelet glycoprotein IX (GP9, also known as CD42a) is a relatively small (17-22 kDa) surface glycoprotein present on platelets and megakaryocytes. GP9 forms a 1:1 non-covalent complex with GPIb (CD42b). The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. Defects in GP9 are a cause of Bernard-Soulier syndrome, also known as giant platelet disease.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"