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Product Name
GNRHR Polyclonal Antibody
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Description
Polyclonal antibody to GNRHR
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Tested applications
WB
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Species reactivity
Human
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Alternative names
GNRHR antibody; GNRHR1 antibody; GRHR antibody; HH7 antibody; LHRHR antibody; LRHR antibody; gonadotropin-releasing hormone receptor antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic Peptide of human GNRHR
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
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Validations
Western blot - GNRHR Polyclonal Antibody
Western blot analysis of extracts of SKOV3 cells, using GNRHR Antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 30s.
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Background
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"