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Product Name
GM2A antibody
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Description
GM2A Rabbit Polyclonal antibody. Positive IHC detected in human colon cancer tissue. Positive IP detected in HEK-293 cells. Positive WB detected in rat kidney tissue, human placenta tissue, mouse kidney tissue. Observed molecular weight by Western-blot: 22 kDa
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Tested applications
ELISA, IHC, WB, IP
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Species reactivity
Human, Mouse, Rat; other species not tested.
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Alternative names
Ganglioside GM2 activator antibody; GM2 AP antibody; GM2 ganglioside activator antibody; GM2A antibody; SAP 3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GM2A recombinant protein (Accession Number: NM_000405). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:111093(GM2A antibody) at dilution of 1:100 (under 10x lens)
rat kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:111093(GM2A Antibody) at dilution of 1:300
IP Result of anti-GM2A (IP:Catalog No:111093, 3ug; Detection:Catalog No:111093 1:600) with HEK-293 cells lysate 2800ug.
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Background
GM2A, also named as GM2-AP and SAP-3, is the large binding pocket which can accommodate several single chain phospholipids and fatty acids. GM2A also exhibits some calcium-independent phospholipase activity. It plays a key role in the degradation of ganglioside GM2 (GM2). GM2A stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"