Glutamine synthetase antibody

Glutamine synthetase antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Glutamine synthetase Mouse Monoclonal antibody. Positive WB detected in Jurkat cells, pig brain tissue, pig liver tissue. Observed molecular weight by Western-blot: 42 kDa

ELISA, WB

Human, Pig; other species not tested.

GLNS antibody; GLUL antibody; Glutamate ammonia ligase antibody; Glutamate decarboxylase antibody; Glutamine synthetase antibody; PIG43 antibody; PIG59 antibody

Mouse IgG2b

This antibody was obtained by immunization of Glutamine synthetase recombinant protein (Accession Number: NM_002065). Purification method: Protein A purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

GLUL(Glutamine synthetase) is also named as GS,GLNS and belongs to the glutamine synthetase family.This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner By similarity. Essential for proliferation of fetal skin fibroblasts(PMID:18662667).Defects in GLUL are the cause of congenital systemic glutamine deficiency (CSGD).Organismal glutamine production is augmented secondary to an increase in the activity of glutamine synthetase in the lung and skeletal muscle(PMID:7630137). There are other bands with higher (66 kDa, 97 kDa) and lower (30 kDa)molecular weights also detected besides the 42 kDa band indicating the proteolysis of GLUL protein by the ubiquitin system(PMID:10091759).