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Product Name
GLRA2 antibody
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Description
GLRA2 Rabbit Polyclonal antibody. Positive WB detected in PBMC cells. Positive IHC detected in mouse brain tissue. Observed molecular weight by Western-blot: 48 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
GLR antibody; GLRA2 antibody; glycine receptor antibody; alpha 2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GLRA2 recombinant protein (Accession Number: NM_001118885). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:300-1:1200
IHC: 1:20-1:200
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Validations
WB result of GLRA2 antibody (Catalog No:111031, 1:600) with PBMC cells. Proteintech αGLRA2 Catalog No:111031 in 10% BSA / TBS 0.05% Tween-20 O/N @ 4°C Goat anti-rabbit HRP 1:10000 in 5% milk / TBS 0.05% Tween-20 1h @ RT.
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:111031(GLRA2 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:111031(GLRA2 Antibody) at dilution of 1:50 (under 40x lens)
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Background
Glycine is an inhibitory neurotransmitter in the central nervous system. The glycine receptor (GlyR) is a member of the nicotinic acetylcholine receptor of ligand-gated ion channels. This receptor has important roles in a variety of physiological processes, especially in mediating inhibitory neurotransmission in the spinal cord and brain stem. GlyR is a pentameric receptor comprised of alpha and beta subunits. Four alpha-subunits (GLRA1, GLRA2, GLRA3, GLRA4) and one beta-subunit (GLRB) of GlyR have been identified. (PMID: 11409700; 15383648)
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