-
Product Name
GLRA1 antibody
- Documents
-
Description
GLRA1 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, mouse cerebellum tissue, SH-SY5Y cells. Observed molecular weight by Western-blot: 48kd
-
Tested applications
ELISA, WB
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
GLRA1 antibody; glycine receptor antibody; alpha 1 antibody; STHE antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of GLRA1 recombinant protein (Accession Number: NM_000171). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
-
Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:111030(GLRA1 antibody) at dilution of 1:500
-
Background
Glycine is an inhibitory neurotransmitter in the central nervous system. The glycine receptor (GlyR) is a member of the nicotinic acetylcholine receptor of ligand-gated ion channels. This receptor has important roles in a variety of physiological processes, especially in mediating inhibitory neurotransmission in the spinal cord and brain stem. GlyR is a pentameric receptor comprised of alpha and beta subunits. Four alpha-subunits (GLRA1, GLRA2, GLRA3, GLRA4) and one beta-subunit (GLRB) of GlyR have been identified. (PMID: 11409700; 15383648)
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"