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Product Name
GLDC antibody
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Description
GLDC Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue. Positive IP detected in mouse liver tissue. Observed molecular weight by Western-blot: 113 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
GCE antibody; GCSP antibody; GLDC antibody; Glycine decarboxylase antibody; HYGN1 antibody; NKH antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GLDC recombinant protein (Accession Number: NM_000170). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
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Validations
mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:111020(GLDC Antibody) at dilution of 1:1000
IP Result of anti-GLDC (IP:Catalog No:111020, 4ug; Detection:Catalog No:111020 1:1000) with mouse liver tissue lysate 4000ug.
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Background
GLDC(Glycine dehydrogenase [decarboxylating], mitochondrial) is also named as GCSP and belongs to the GcvP family. It induces dramatic changes in glycolysis and glycine/serine metabolism that leads to changes in pyrimidine metabolism to regulate cancer cell proliferation(PMID:22225612).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"