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Product Name
GKN1 antibody
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Description
GKN1 Mouse Monoclonal antibody. Positive WB detected in Human stomach. Observed molecular weight by Western-blot: 18-20kd
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Tested applications
ELISA, WB
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Species reactivity
human; other species not tested.
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Alternative names
GKN1 antibody; Protein CA11 antibody; 18 kDa antrum mucosa protein antibody; foveolin antibody; FOV antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of GKN1 recombinant protein (Accession Number: BC059778). Purification method: Caprylic acid/ammonium sulfate precipitation.
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Clonality
Monoclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
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Validations
human stomach tissue were subjected to SDS PAGE followed by western blot with Catalog No:107298(GKN1 antibody) at dilution of 1:400
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Background
Gastrokine 1 (GKN1), a stomach-specific protein also known as 18 kDa antrum mucosa protein (AMP-18) or foveolin, belongs to the gastrokine family of gastric mucus cell-secreted proteins. The human GKN1 gene has been localized in a region of chromosome 2p13 of about 6 kb and contains 6 exons. GKN1 is expressed only in normal human stomach, but is absent from gastric adenocarcinomas, gastro-esophageal adenocarcinoma cell lines, and other normal and tumor gastro-intestinal tissues. GKN1may play an important role in normal gastric function and may be a gastric tumour suppressor.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"