GATA4 Monoclonal Antibody

GATA4 Monoclonal Antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Monoclonal antibody to GATA4

WB, IHC, IF, IP

Human, Mouse, Rat

GATA4 antibody; ASD2 antibody; TACHD antibody; TOF antibody; VSD1 antibody; GATA binding protein 4 antibody

Mouse IgG

Antigen: A synthetic peptide of human GATA4

Monoclonal

PBS with 0.02% sodium azide, pH7.3.

Store at 4℃. Avoid freeze / thaw cycles.

WB 1:200 - 1:500
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:100

Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity). Promotes cardiac myocyte enlargement. Required during testicular development. May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase.